Andrea I. Doseff
Associate Professor | Medicine and Molecular Genetics
305B Davis Heart & Lung Inst.,
473 W. 12th Ave.,
Areas of Expertise
- Cell death during the innate immune response
- Oncogenic transformation
- Ph.D., Genetics, Cold Spring Harbor Laboratory and State University of New York (1996)
- B.S., Biology, University of Buenos Aires (1987)
Andrea I. Doseff is an Associate Professor of Medicine and Molecular Genetics. Dr. Doseff's labratory investigates the mechanisms involved in cell death during the innate immune response and oncogenic transformation. Her lab combines molecular, biochemical, cellular biology and bioinformatics approaches to understand the regulation of the apoptotic pathways.
Her studies are focused on the signaling pathways that contribute to the activation and deactivation of caspases, essentials proteases required for apoptosis. The main purpose of her research is that by understanding the mechanisms that regulate the caspases we will be able to manipulate cell death of unwanted cells as a treatment for cancer, inflammation and formation of the atherosclerotic plaque.